Searchable abstracts of presentations at key conferences in endocrinology

ea0026p259 | Pituitary | ECE2011

Predictive markers of recurrence in radically resected pituitary macroadenomas

Curto L , Ruggeri R M , Cotta O R , Ragonese M , Ieni A , Puglisi S , Costanzo D , Trimarchi F , Cannavo Salvatore

Introduction: Pituitary adenomas are benign neoplasms which grow slowly, but that can recur even after apparent radical resection. Until now, markers predicting regrowth and invasiveness have not been completely characterized.Design: We investigated cell proliferation and apoptosis parameters in 20 radically resected pituitary macroadenomas (six GH, two PRL, two ACTH, one FSH and nine non-secreting), in order to predict recurrence risk. Tumour regrowth w...

ea0026p270 | Pituitary | ECE2011

Primary empty sella is associated with increased cardiovascular risk, regardless the occurrence of pituitary dysfunction

Torre M L , Cotta O R , Ferrau F , Di Mauro E , Albani A , Boschetti M , Teti C , Savanelli M C , Di Somma C , Alibrandi A , Ferone D , Cannavo S , Colao A

Introduction: Primary empty sella (PES) is a frequent ‘incidental’ finding reported in 5–25% of general population and is associated with endocrine abnormalities in 8–60% of cases. In this collaborative multicentric study we evaluated cardiovascular risk by assessing clinical characteristics, glucidic profile and lipid parameters.Design: A total of 94 PES patients (39M-55F; mean age 50.3±0.9 years; mean BMI 28.9±0.5 kg/m<sup...